Dynamic simulation of the human red blood cell metabolic network

نویسندگان

  • Neema Jamshidi
  • Jeremy S. Edwards
  • Tom Fahland
  • George M. Church
  • Bernhard O. Palsson
چکیده

We have developed a Mathematica application package to perform dynamic simulations of the red blood cell (RBC) metabolic network. The package relies on, and integrates, many years of mathematical modeling and biochemical work on red blood cell metabolism. The extensive data regarding the red blood cell metabolic network and the previous kinetic analysis of all the individual components makes the human RBC an ideal 'model' system for mathematical metabolic models. The Mathematica package can be used to understand the dynamics and regulatory characteristics of the red blood cell.

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عنوان ژورنال:
  • Bioinformatics

دوره 17 3  شماره 

صفحات  -

تاریخ انتشار 2001